R&D Areas of Interest
 We are seeking external alliances in both
the pre-clinical discovery and the clinical development
phases of research. Specifically, novel
compounds/targets and relevant in vitro/in vivo
models in each of the following therapeutic areas are of
interest:
Oncology
- apoptosis
- cell cycle control
- proliferation/angiogenesis
- immune stimulation
- motility/invasion
- chemoprevention
Cardiovascular/Metabolism
- vascular disease prevention (inflammation, vascular cell
function)
- thromboembolism (anticoagulants, antiplatelets)
- dyslipidemia (insulin-resistance syndrome, new
lipid-lowering agents)
- antiarrhythmics
- obesity
- diabetes
Central Nervous System
- Alzheimer’s and Parkinson’s diseases, multiple
sclerosis (amyloidosis, neuro-restoration and anti-neuroinflammation strategies, surrogate markers)
- novel molecular approaches in depression, schizophrenia
and anxiety
Gastrointestinal
- reflux disease
- irritable bowel syndrome
- inflammatory bowel disease
- functional dyspepsia
- prevention of H. pylori infection
Respiratory/Inflammation
- asthma/chronic obstructive pulmonary disease (activation
of mast, fibroblast, and macrophage cells, neurogenic
inflammation)
- rheumatoid and osteoarthritis (immune modulation, angiogenesis, cartilage repair, bone destruction and remodeling)
- psoriasis/transplant rejection (T-cell trafficking/co-stimulation)
Pain Control
- novel G-protein-coupled receptors in central nervous
system
- voltage- and ligand-gated ion channels
- analgesic approaches including opioid receptors
- animal models of pain control
Infection
- antibacterials/antifungals
Enabling Technology
- transgenic animal models
- functional genomics
- bioinformatics/proteomics
- drug delivery systems
- higher capacity high throughput screening
- stem cell technology
For more information, please send an e-mail to research
liaison.
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